PREPARATION OF SULFATED CHITOSAN AND SULFATING AGENT FOR CHITOSAN

摘要

PURPOSE: To provide a process for preparing a sulfated chitosan having high purity and high viscosity and being useful in the fields of pharmaceutical and cosmetic preparations, etc., easily at a low cost through a simplified refining step. ;CONSTITUTION: Regenerated chitosan botd. by neutralizing an aq. acid soln. of chitosan in a polar solvent capable of solubilizing an SO₃-trialkylamine complex without decomposition thereof is reacted with the SO₃-trialkylamine complex to selectively sulbate the C-3 and C-6 hydroxyl groups of chitosan.;COPYRIGHT: (C)1994,JPO&Japio