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A NUCLEIC ACID WHICH CODES HUMAN AMINO ACID SEQUENCES.

机译:编码人类氨基酸序列的核酸。

摘要

Lymphotoxin (I) absolutely free from homologous proteins that are unidentified or present in unknown amounts is new. Unglycosylated (I) is new. Variant (I) in which an amino acid residue in the (I) sequence has been deleted or substd. by another residue, or in which another residue has been inserted, is new. Provided that (I) having a sequence with an amino terminal at Leu(+)1 or His(+)23 is excluded. Nucleic acid encoding (I) and selected from (a)-(c) is new. (a) DNA encoding (I) free from DNA encoding other proteins of the organism from which the DNA originated; (b) DNA encoding (I) free from untranslated intervening sequences; and (c) nucleic acid capable of hybridising to nucleic acid encoding (I), provided that the acid does not have the nucleotide sequence of natural DNA or RNA encoding (I).
机译:绝对不含未知蛋白或未知数量的同源蛋白的淋巴毒素(I)是新的。未糖基化(I)是新的。变体(I),其中(I)序列中的氨基酸残基已被缺失或取代。另一个残基或已插入另一个残基的术语是新的。前提是(I)具有在Leu(+)1或His(+)23具有氨基末端的序列的被排除。编码(I)并选自(a)-(c)的核酸是新的。 (a)编码(I)的DNA,不含编码该DNA来源的生物体其他蛋白质的DNA; (b)编码(I)的DNA不含未翻译的插入序列; (c)能够与编码(I)的核酸杂交的核酸,条件是该酸不具有编码(I)的天然DNA或RNA的核苷酸序列。

著录项

  • 公开/公告号AR245219A1

    专利类型

  • 公开/公告日1993-12-30

    原文格式PDF

  • 申请/专利权人 GENENTECH INC.;

    申请/专利号AR19860305572

  • 发明设计人

    申请日1986-10-14

  • 分类号C12N15/11;C12P21/00;A61K45/05;C07H21/04;C07K15/04;C07K15/06;5C12R1:19B;

  • 国家 AR

  • 入库时间 2022-08-22 04:46:46

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