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Immunogenic conjugate, process for their preparation, AND VACCINE COMPRISING SUCH POLYMER CONJUGATE AND capsular FRAGMENT FOR THE MANUFACTURE OF conjugate
Immunogenic conjugate, process for their preparation, AND VACCINE COMPRISING SUCH POLYMER CONJUGATE AND capsular FRAGMENT FOR THE MANUFACTURE OF conjugate
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机译:免疫原性缀合物,其制备方法以及包含用于制备缀合物的这种聚合物缀合物和荚膜片段的疫苗
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摘要
The invention relates to immunogenic conjugates of E. coli LT-B enterotoxin subunit and capsular polymers, methods for the preparation of the conjugates, a vaccine containing the conjugates which elicits effective levels of anti-capsular polymer antibodies in humans. Also disclosed are methods for including active immunization against systemic infection in young mammals caused by bacterial pathogens comprising the administration of an immunogenic amount of the above-described conjugate.
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