Avermectin derivatives, the compounds for use in veterinary medicine, to compositions containing the compounds, their use for the preparation of ectoparasitcide, insecticidal, acaricidal or anthelmintic drugs, and non-therapeutic method for controlling pests in crops

摘要

Antiparasitics comprising Avermectin derivatives of formula (I): CHEM wherein the broken line between the 22-23 position represents an optional double bond and wherein either R1 is H or OH and the double bond is absent, or the double bond is present and R1 is absent; R2 is a C1-C6 alkyl group substituted by one oxo or one or more hydroxy groups or by a single oxygen atom on two adjacent carbon atoms to form an oxirane ring, or R2 is a C1-C5 alkyl group substituted by a (C1-C6 alkoxy) carbonyl group, said substituents on R2 being attached to either or both a terminal carbon atom and a carbon atom adjacent to a terminal. carbon atom of R2; and R3 is H or CH3; or, when R2 is substituted by oxo, a (C1-C4 alkyl) acetal or ketal derivative thereof.