The protection of equines against streptococcus equi

摘要

A new bacterial vaccine to protect susceptible equine against S. equi which causes strangles. The vaccine stimulates a nasopharyngeal immune response in a susceptible equine through the presence of antibody activity in the nasopharyngeal mucus. The vaccine is a S. equi strain which contains an M protein fragment of 41,000 mw and is adapted for administration to equine either intranasally or orally as a vaccine. There is described a new strain of S. equi (709-27), a method of making and isolating useful vaccine strain of S. equi bacteria which stimulates an antibody response in the nasopharyngeal mucosa of the susceptible equine.