Atypical neuroleptic composition comprising 5-chloro-1- (4-fluorophenyl) -3-(1-(2-(2-imidazolidinon-1-yl) ethyl)-4-piperidyl) -1h-indole

摘要

Described is the use of 5-chloro-1-(4-fluorophenyl)-3-(1-(2-(2-imidazolidinon-1-yl)ethyl)-4-pi peridyl)-1H-indole , or a pharmaceutically acceptable acid addition salt thereof, for the manufacturing of a pharmaceutical composition selectively blocking dopamine neurones in the ventral tegmental area in the brain, substantially without inhibiting the activity of dopamine neurones in substantia nigra pars compacta.