Pan-sink for s-541 antibiotic s-541 streptomycete strain-antibiotic producers

摘要

The invcution relates to a new combination of autibiotics and the reception method, more concret3 the invention relates to combination of antibiotics, which could be received through the fermentation of antinoyces streptomeces thermoarchaensis of the strais NC 1B12015 or NC1B12111 or NC 1B12114 in medium which contains a carbon, axot and mineral salty source at 28-34°C, pH 5,4-7,2 during 5-10 days with subsequent elimination of the antibiotic whole product S541 of formula; in which R1 is methyl, ethyl ar isopropyl; R1 is hydrogen or methyl.