DNA Molecule encoding Lipase or Bile Salt stimulated Lipase carboxilicobiologicamente Functional Ester and Method for Lipase Production stimulated by Bile Salt and LipHandle of carboxylic Ester.

摘要

The present Invention relates to a DNA Molecule that contains sequences of Intron and encodes a Protein of Human which is, depending on the site of Action,Called Lipase stimulated by Bile salt (LESB) or carboxylic Ester Lipase (LEC).The DNA Molecule is used to Advantage in the production of recombinant human Lesb / LEC, preferably by means of production in Transgenic non-human mammals.The Recombinant human Lesb / LEC can be used as a constituent of Infant formulas used for feeding infants as a substitute for Human Milk or in manUfactura Drugs, for example, Fat malabsorption, fibru00f3sis cystic and chronic pancreatitis.