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METHOD FOR MANUFACTURING PLASTER AS A TRANSDERMAL THERAPEUTIC SYSTEM FOR APPALYING THERAPEUTICAL SUBSTANCES THROUGH SKIN WITH GRADUAL RELEASE
METHOD FOR MANUFACTURING PLASTER AS A TRANSDERMAL THERAPEUTIC SYSTEM FOR APPALYING THERAPEUTICAL SUBSTANCES THROUGH SKIN WITH GRADUAL RELEASE
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机译:制造作为透皮治疗系统的膏药的方法,该透皮治疗系统通过皮肤将治疗性物质应用到皮肤中
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摘要
Transdermal patches for controlled release of a drug comprise at least one drug reservoir in contg. with a drug-contg. release-controlling matrix, with a backing layer on the skin-distal side of the matrix and an adhesive layer on the skin-proximal side. The size and posn. of each drug reservoir are such that in at least one direction, the distance between the reservoir and the drug delivery surface of the matrix is greater than the diffusion path length of at least one drug from its reservoir into the matrix during the period of application.
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