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pyridoxamin - chelate compounds, manganese (ii chelate and their use as nmri contrast.
pyridoxamin - chelate compounds, manganese (ii chelate and their use as nmri contrast.
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机译:吡ido胺-螯合物,锰(ii螯合物及其作为nmri对比剂的用途。
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摘要
Manganese(II) chelates of N,N min -bis-(pyridoxal)alkylenediamine-N,N min -diacetic acids, N,N min -bis-(pyridoxal)-1,2-cycloalkylenediamine-N,N min -diacetic acids, N,N min -bis-(pyridoxal)-1,2-arylenediamine-N,N min -diacetic acids, N,N min -bis-(pyridoxal)alkylenediamine-N-acetic acids, N,N min -bis-(pyridoxal)-1,2-cycloalkylenediamine-N-acetic acids, N,N min -bis-(pyridoxal)-1,2-arylenediamine-N-acetic acids, and their salts are highly stable, superior NMRI contrast agents. They maintain the manganese(II) ion in the +2 valence state. Preferred contrast agents are manganese(II) ion chelates of N,N min -bis-(pyridoxal)ethylenediamine- N,N min -diacetic acid, N,N min -bis-(pyridoxal)trans-1,2-cyclohexylenediamine-N,N min -diacetic acid, and the salts and esters thereof. Novel chelate forming compounds are the N,N min -bis-(pyridoxal)-1,2-cycloalkylenediamine-N,N min -diacetic acids and N,N min -bis-(pyridoxal)-1,2-arylenediamine-N,N min -diacetic acids, N,N min -bis-(pyridoxal)alkylenediamine-N-acetic acids, N,N min -bis(pyridoxal)-1,2-cycloalkylenediamine-N-acetic acids, N,N min -bis-(pyridoxal)-1,2-arylenediamine-N-acetic acids, and their salts and esters.
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