ANTIBODIES AGAINST HIGH-CONSERVED AMINO ACID SEQUENCES OF IMMUNOGENOUS SUBSTANCES, METHOD FOR THE PRODUCTION OF THESE ANTIBODIES, AND THEIR USE IN IMMUNOASSAYS.

摘要

The invention relates to antibodies which are obtained by immunisation with a peptide fragment which represents a highly conserved amino-acid sequence of a natural protein. The antibodies according to the invention can be used to produce immunoassays, in particular to produce assays for the determination of genetically engineered products such as insulin, which are produced as sparingly soluble inclusion bodies in microorganisms. The invention particularly relates to a multispecies insulin assay in the form of an RIA.