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thiadiazole usable for the treatment of age-related dementia.
thiadiazole usable for the treatment of age-related dementia.
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机译:噻二唑可用于治疗老年性痴呆。
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摘要
A class of novel thiadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring system, and substituted on the other ring carbon atom with a substituent of low lipophilicity, or a hydrocarbon substituent; are potent muscarinic agonists, and have good CNS penetrability. The compounds are therefore useful in the treatment of neurological and mental illnesses, and are also of benefit in the treatment of severe painful conditions.
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