17-aza new derivatives of 20,21-dinoreburnamenin and novel intermediates of preparation, their use as medicaments and compositions containing them.

摘要

The invention relates to compounds of formula (I) wherein R1 and R2 represents hydrogen, alkoyl or C1-C5, hydroxy, trifluoromethyl or nitro, R represents hydrogen, alkoyl C1-C5, ARILALCOILO C7-C12, ALCOILCARBONILO benzoyl or Y (II) under all isomeric forms POSSIBLE racemic or optically active as salts with acids, preparation method, its application as medicaments and new intermediaries.