NOVEL RECOMBINANT DNA, PRODUCTION OF MINK GROWTH HORMONE, AND A DNA FRAGMENT USED TO EXPRESS MINK GROWTH HORMONE GENE AND TO SECRETE MINK GROWTH HORMONE

摘要

ABSTRUCT Mink growth hormone gene is expressed by using a synthetic DNA encoding a pre-sequence derived from neutral protease II gene of Aspergillus oryzae, a pro-sequence consisting of 7 amino acids and a Kex 2 recognition amino acid sequence. According to the present invention, mink growth hormone is efficiently produced in a short period of time.