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HUMAN CNS RECEPTORS OF THE NMDA-R1 FAMILY
HUMAN CNS RECEPTORS OF THE NMDA-R1 FAMILY
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机译:NMDA-R1家族的人类CNS受体
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摘要
Neurotransmission by excitatory amino acids (EAAs) such as glutamate is mediated via membrane-bound surface receptors. DNA coding for EAA receptors of one family of human NMDA-binding type receptors has now been isolated and receptor proteins characterized. Herein described are recombinant cell lines which produce the EAA receptor as a heterologous membrane-bound product. Also described are related aspects of the invention, which are of commercial significance. Included is use of the cell lines as a tool for discovery of compounds which modulate EAA receptor stimulation.
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