PURPOSE: To obtain a new polynucleotide for the screening assay of a compound useful for the treatments of a human CNS diseases. ;CONSTITUTION: An isolated polynucleotide containing a nucleotide sequence encoding a human NMDAR 1 receptor or its fragment exhibiting at least one of MK-801 bond or a glutamate bond, such as a polynucleotide encoding human NMDAR 1-1 receptor. The polynucleotide is obtained by a recombination DNA method.;COPYRIGHT: (C)1994,JPO
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