NOVEL CHELATING AGENT, COMPLEX COMPOUND OF SAID CHELATING AGENT AND METALLIC ATOM, AND DIAGNOSTIC AGENT COMPRISING SAME

摘要

A compound of the following formula IMG wherein m is an integer of 1 to 3, R1 and R2 are the same or different and each is hydrogen atom or lower alkyl, and R3, R4, R5 and R6 are the same or different and each is hydroxy or a group of the formula IMG (wherein n is 0 or 1, X is -NH- or -O-, Y is alkylene, A is hydrogen atom, lower alkyl, lower alkoxy, halogen atom or trifluoromethyl, and B is alkyl or alkenyl), with the proviso that two or three of R3, R4, R5 and R6 are hydroxyl groups and that when two of them are hydroxyl groups, the cases where R3 and R5 are hydroxy, and R4 and R5 are hydroxy are excluded; a complex compound comprising said compound and a metallic atom; and a diagnostic agent containing said complex compound. The above compound is useful as a chelating agent and the complex compound comprising said compound and a metallic atom exhibits superior characteristics as a contrast medium for image diagnosis.