FuroÝ3,2-b¨pyridines and thienoÝ3,2-b¨pyridines as inhibitors of leukotriene biosynthesis

摘要

Compounds having the formula I: IMAGE I are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomemlar nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.