首页> 外国专利> RADIOACTIVE IODINE- OR BROMINE LABELLED PIPERIDINE COMPOUND AS WELL AS METHOD OF PREPARING SAME AND COMPOSITION COMPRISING SAID COMPOUND

RADIOACTIVE IODINE- OR BROMINE LABELLED PIPERIDINE COMPOUND AS WELL AS METHOD OF PREPARING SAME AND COMPOSITION COMPRISING SAID COMPOUND

机译:放射性碘或溴标记的哌啶化合物及其制备方法和包含所述化合物的组合物

摘要

the invention relates to a compound of piperidine in iodine or bromine radioactive, having the general formula (i), in which there is a radioactive iodine atom) or a bromine atom, q represents a radioactive; group derived from a heterocyclic ring system, comportan two ring annulation.which include at least two atoms together straight choisisdans group consisting of n, o, and s, the ring system is replaced by at least one oxo - and / or thioxo function and can be replaced by one or more substituents selected from the group consisting of alkyl of c1 c4, c1-c4 alkoxy, halogen, c1-c4 alcoylamino di (c1 - c4) and alcoylamino.the invention relates to a preparation process of the compound, a composition comprising the compound, a radiopharmaceutical kit preparation, as well as of the composition.
机译:本发明涉及一种在放射性碘或溴中的哌啶化合物,其通式为(i),其中有放射性碘原子或溴原子,q表示放射性;由杂环系统衍生的基团,包括至少两个原子一起由n,o和s组成的直碳原子团,由至少一个oxo-和// thioxo官能团取代,并且可以被一个或多个选自以下的取代基取代:c 1 -c 4,c 1 -c 4烷氧基,卤素,c 1 -c 4烷氨基二(c 1 -c 4)和烷氨基的烷基。本发明涉及该化合物的制备方法,包含所述化合物的组合物,放射性药物试剂盒制剂以及所述组合物。

著录项

  • 公开/公告号EP0460118A4

    专利类型

  • 公开/公告日1994-01-12

    原文格式PDF

  • 申请/专利权人 MALLINCKRODT INTERNATIONAL CORPORATION;

    申请/专利号EP19900907738

  • 发明设计人 MERTENS JOHN;

    申请日1990-03-22

  • 分类号A61K49/02;

  • 国家 EP

  • 入库时间 2022-08-22 04:39:43

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