PROCESS FOR PREPARING CARRIER FOR CATION EXCHANGE LIQUID CHROMATOGRAPHY AND METHOD OF QUANTITATIVELY DETERMINING GLYCOSYLATED HEMOGLOBIN USING SAID CARRIER

摘要

A process for preparing a carrier suitable for use in a cation exchange liquid chromatography, which comprises a step of providing a hydrophobic particle having a polymerization initiator adherent thereto, and a step of adding a polymerizable monomer having a carboxyl group to a dispersion of the hydrophobic crosslinked polymer particle in water, polymerizing the monomer on the surface of the polymer particle, thereby preparing a coated polymer particle comprising a hydrophobic crosslinked polymer particle and, formed on the surface thereof, a layer of a polymer having a carboxyl group