Captopril sustained-release tablets and methods for their preparation

摘要

The present invention relates to a sustained release pharmacological action of captopril and a method for its preparation. The sustained-release tablet of caprofur according to the present invention can be prepared by dissolving caprofuryl, an antioxidant such as hydroxyethylcellulose, an ascorbic acid, which is an agent for improving the adhesion of the gastrointestinal tract, stearyl alcohol and hydrolyzed castor oil as a lipophilic base, and magnesium stearate And stearic acid. The sustained-release tablet of the present invention may also be coated with a moisture-proof film coating.;The captopril sustained release tablets according to the present invention can remain in the drug absorption site for a longer period of time, so that a smaller amount of captopril can be used and the effective drug concentration can be maintained for a longer period of time.