2-Carbapenem derivs. for formula (I) are new. n = O or 1; R = H or a radical forming an ester hydrolyzable under physiological conditions; and R1 = H or Me; or a pharmaceutically acceptable cationic salt thereof when R = H. - Also claimed are intermediates of formula (II). R4 = carboxylic acid protecting gp. Pref. R is (5-methyl -1,3-dioxol-2-on-4-yl)methyl, 1H-isobenzofuran-3-on-1-yl, gamma-butyrolacton-4-yl, -CH2R2OCOR3, or -CHR2OCOOR3; R2 = H or Me; R3 = 1-6C alkyl. R is most pref. pivaloyloxymethyl or 1-(ethoxycarbonyloxy)ethyl. R4 is pref. -CH2CX=CH2.
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机译：2-碳青霉烯衍生物。式（I）的化合物是新的。 n = O或1; R ＝ H或形成在生理条件下可水解的酯的基团; R1 = H或Me;当R ＝ H时，或其药学上可接受的阳离子盐。-还要求保护的是式（II）的中间体。 R 4 ＝保护羧酸的gp。首选R为（5-甲基-1,3-二氧杂-2-基-4-基）甲基，1H-异苯并呋喃-3-基-1-基，γ-丁内酯-4-基，-CH2R2OCOR3或-CHR2OCOOR3; R2 = H或Me; R 3 ＝ 1-6C烷基。 R是最喜欢的。新戊酰氧基甲基或1-（乙氧基羰氧基）乙基。 R4是首选。 -CH2CX = CH2。
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