Method for quantification of brain volume from magnetic resonance images

摘要

A simple, rapid and semi-automated method of MRI analysis based on mathematical modelling of MRI pixel intensity histograms. The method is accurate and reliable for regional analysis of brain, central and subarachnoid CSF volumes. The method can be used to reveal significant age-related changes in regional brain volumes which cannot be determined utilizing traced central CSF volumes or subarachnoid CSF volumes. The method can be used to quantify brain structure in healthy aging and brain disease.