Process for purifying and characterizing myotrophia, a novel peptide that regulates myocardial growth

摘要

The present invention is directed to a process for purifying and characterizing "myotrophin", a novel soluble protein factor that is believed to regulate myocardial hypertrophy in hypertension. In addition, the invention is directed to the purified and partially characterized protein factor produced by the process of the present invention, as well as uses of this factor, or its antagonist to control cardiac hypertrophy.