ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS

摘要

Preparation of compounds of sulfenamida - 6, 6 - sulfinamida purines and purine nucleotide and nucleoside of formula (i), where z is H OR - NH2; X is formula (ii); g, T and q are C - H OR N,E and esh or an alpha pentofuranosa of formula (iii), where R1 and R2 are h, Oh, o - Acyl - or Group a or B are set R1 and R2, R3 and R4 are H or one of R3 or R4 is o and the other is H, and is H,Is that - NH2, comprising reacting compounds of formula (iv) with the corresponding compounds to form Chloramine, where X is a Group snh2, which is then oxidized with an oxidizing Agent.