Composition for prophylaxis and treatment of myopia and process to produce aqueous eye drops

摘要

A use of a compound of the formula CHEM wherein R is an alkyl, R1 is a hydrogen or an amino and R2 is a carboxyl or a tetrazole, or a salt thereof for the production of a composition for the prophylaxis and treatment of myopia. The use for the prophylaxis and treatment of myopia of the present invention not only results in relaxing action on the ciliary smooth muscle of rabbit, but also brings about superior effects of prevention and treatment of myopia of the patients on whom Mydrin-M, a conventional preparation for the prophylaxis and treatment of myopia, failed to have effects. In addition, the use does not involve a mydriatic response and is advantageous for the prophylaxis and treatment of myopia.