3-SUBSTITUTED PYRROLIDINE DERIVATIVE, PROCESS OF ITS PREPARATION, INTERMEDIATES OF SUCH PROCESS AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF

摘要

Pyrrolidine derivatives of the general formula I are described in which Y represents a direct bond, -CH.sub.2- or - (CH.sub.2.). R is -CN or -CONH 2, and R 5 is n. heterocyclic group, process for their preparation, intermediates of this process of formula II and IV, and pharmaceutical compositions containing these derivatives. These compounds are muscarinic receptor antagonists and are useful in the treatment of motility and / or smooth muscle tone disorders, such as irritable bowel syndrome, diverticular disease. urinary incontinence, esophageal achalasia, and chronic obstructive bronchopulmonary disease.ŕ