Process for the preparation of dyes or monacholine K in water-poor, sterile fluidized bed

摘要

The process entails cultivation of a microorganism of the genus Monascus in a water-depleted, sterilisable fluidised bed fermenter as has been proposed in German Patent Application P 36 25 698.6. The microorganism itself - in pellet form or grown on carriers - is used as fluidisable particle and can be supplied with nutrients by spraying substrate solutions in. The dyes and/or active substances are isolated by extraction with organic solvents.