首页> 外国专利> PROCESS FOR PRODUCING PHARMACEUTICAL COMPOSITIONS CONTAINING SUBSTITUTED 3,4-DIHYDRO-2H-BENZOPYRANES AS ACTIVE COMPONENT FOR TREATING OBSTRUCTIVE FUNCTIONAL DISORDERS OF THE LUNGS AND THE RESPIRATORY SYSTEM

PROCESS FOR PRODUCING PHARMACEUTICAL COMPOSITIONS CONTAINING SUBSTITUTED 3,4-DIHYDRO-2H-BENZOPYRANES AS ACTIVE COMPONENT FOR TREATING OBSTRUCTIVE FUNCTIONAL DISORDERS OF THE LUNGS AND THE RESPIRATORY SYSTEM

机译:生产包含取代的3,4-二氢-2H-苯并吡喃类药物的药物组合物的方法

摘要

A description is given of the use of 3,4-dihydro-2H-benzo[b]pyrans of the formula I …IMAGE… in which… R1 is H, OH, (C1-C2)-alkoxy, (C1-C2)-alkyl or NR4R5 where R4 and R5 are identical or different and are H, (C1-C2)alkyl or (C1-C3)-alkylcarbonyl,… R2 and R3 are identical or different and are alkyl with 1 to 4 C atoms,… Ar is an aromatic or heteroaromatic system which is unsubstituted or substituted by 1 to 3 identical or different radicals (C1-C2)-alkyl, (C1-C2)alkoxy, halogen, trifluoromethyl, CN, NO2, CO-(C1-C2)alkyl or SOm-(C1-C2)-alkyl with m = 1 or 2,… n is 1 or 2,… X is a chain (CH2)r which can be interrupted by a hetero atom O, S or NR6 where R6 is H or (C1-C4)-alkyl, and r is the numbers 2, 3, 4 or 5,… for the preparation of a medicament against obstructive functional disorders of the lungs and/or disorders of the urinary tract.
机译:给出了式I……的3,4-二氢-2H-苯并[b]吡喃的用途的描述,其中... R 1是H,OH,(C1-C2)-烷氧基, (C1-C2)-烷基或NR 4 R 5,其中R 4和R 5相同或不同,且为H,(C1-C2)烷基或(C1-C3)-烷基羰基,… R 2和R 3是相同或不同的,并且是具有1-4个C原子的烷基,…Ar是未被取代或被1-3个相同或不同的基团(C1-C2)取代的芳族或杂芳族系统-烷基,(C1-C2)烷氧基,卤素,三氟甲基,CN,NO2,CO-(C1-C2)烷基或SOm-(C1-C2)-烷基,m = 1或2,…n为1或2,… X是可以被杂原子O,S或NR 6中断的链(CH 2)r,其中R 6是H或(C1-C4)-烷基,并且r是数字2、3、4或5,…用于制备抗阻塞性肺功能障碍和/或尿路疾病的药物。

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