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(-) AND (+) 10-(1-AZABICYCLO2,2,2OCT-3-YL-METHYL)-10 H-PHENOTHIAZINE QUATERNARY AMMONIUM DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PRODUCING THEM
(-) AND (+) 10-(1-AZABICYCLO2,2,2OCT-3-YL-METHYL)-10 H-PHENOTHIAZINE QUATERNARY AMMONIUM DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PRODUCING THEM
The description refers to dextrorotatory (+) and levorotatory (-) enantiomorphs of quaternary ammonium derivatives of 10-(1-azabicyclo[2.2.2.]oct-3-yl-methyl)-10 H-phenothiazine as per general formula (I), where R = C1-4 alkyl, cyclopropyl, X = halogen, dimethyl sulphate, p-toluenesulphonic acid as well as to the preparation of same and to the pharmaceutical compositions containing them.
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机译:该描述涉及根据通式(I)的10-(1-氮杂双环[2.2.2。]辛-3-基-甲基)-10 H-吩噻嗪季铵衍生物的右旋(+)和左旋(-)对映体。 ),其中R = C 1-4烷基,环丙基,X =卤素,硫酸二甲酯,对甲苯磺酸及其制备方法和含有它们的药物组合物。
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