首页> 外国专利> Recombinant and native group b eimeria tenella immunogens useful as coccidiosis vaccines

Recombinant and native group b eimeria tenella immunogens useful as coccidiosis vaccines

机译:重组和天然b组艾美球虫Tenella免疫原可用作球虫病疫苗

摘要

Genes coding for novel Group B Eimeria tenella protein immunogens have been isolated and inserted into a novel expression vector which in turn has been used to transform appropriate hosts. The transformed host cells produce recombinant Group B E. tenella proteins which are capable of inducing immunity in chickens to coccidiosis. Antibody prepared against the recombinant protein immunogens is used to isolate and identify the native protein from disrupted E. tenella sporulated oocysts.
机译:已经分离出编码新的B族艾美氏球菌蛋白质免疫原的基因,并将其插入新的表达载体中,该载体又被用于转化合适的宿主。转化的宿主细胞产生重组B. E. tenella蛋白,该蛋白能够诱导鸡对球虫病的免疫力。针对重组蛋白免疫原制备的抗体用于从破坏的大肠杆菌分离的卵囊中分离和鉴定天然蛋白。

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