PROCESS FOR THE PREPARATION OF 1-DEOXYNOJIRIMYCIN FROM 1,2-O-ISLPROPYLIKENE-5-OXO- a-D-GLUCURONOLACTONE

摘要

The present invention relates to an efficient new route for the preparation of (+)-nojirimycin and (+)-1-deoxynojirimycin which involves the stereoselective reductive amination of 1,2-O-isopropylidene- 5-oxo-. alpha.-D-glucuronolactone. The reductive amination uses particular oximes of the 5-oxo compound.