APPLICATION OF BENZIMIDAZOLE DERIVATIVES, NOVEL BENZIMIDAZOLE DERIVATIVES, PHARMACEUTIC AGENT AND METHOD OF OBTAINING BENZIMIDAZOLE DERIVATIVES

摘要

This invention provides novel substituted benzimidazoles of formula II which are useful as tachykinin receptor antagonists. This invention also provides methods for treating a condition associated with an excess of tachykinin which comprises administering to a mammal in need thereof one of a series of substituted benzimidazoles. This invention further provides pharmaceutical formulations comprising one or more of the substituted benzimidazoles of the present invention in association with pharmaceutical carriers, diluents, or excipients. CHEM A and Ra-Re are as defined in the description.