COMPLEX OF PLEUROMULTILINE DERIVATIVE AND CYCLODEXTRINE, METHOD OF ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THIS COMPLEX

摘要

Complexes and pharmaceutical preparations containing complexes of the pleuromutilin derivative of formula I CHEM in free base or in acid addition or quaternary salt form and cyclodextrin are described. They can be prepared by complexing the above pleuromutilin compound with an appropriate cyclodextrin. They are indicated for use as pharmaceuticals, e.g. as antibiotics, especially in veterinary medicine, e.g. as feed additives.