首页> 外国专利> PROCESS FOR PRODUCING BETA-DELTA-PHENYLTHIOXYLOSIDES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS AS ACTIVE INGREDIENT

PROCESS FOR PRODUCING BETA-DELTA-PHENYLTHIOXYLOSIDES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS AS ACTIVE INGREDIENT

机译:制备包含此类化合物作为活性成分的β-δ-苯甲氧基苯氧化物和药物组合物的方法

摘要

The present invention relates, by way of novel industrial products, to the beta -D-phenylthioxyloside compounds of the formula IMAGE (I) in which: X represents a sulfur atom or an oxygen atom; R1, R2 and R3, which are identical or different, each represent a hydrogen atom, a nitro group, a cyano group, a group -CO-R (in which R represents a C1-C4 alkyl group or a trifluoromethyl group), an amino group, an acetamido group (NHCOCH3), a C1-C4 alkoxy group, a trifluoromethyl group or a phenyl group substituted by one or more cyano, nitro or trifluoromethyl groups, it being possible for R1 and R2, taken together, to form, with the phenyl group to which they are bonded, a beta -naphthalenyl group which is unsubstituted or substituted by one or more cyano, nitro or trifluoromethyl groups; and Y represents the hydrogen atom or an aliphatic acyl group. These compounds are useful as therapeutic agents, especially as venous antithrombotics.
机译:本发明涉及通过新型工业产品的式(I)的β-D-苯基硫代木糖苷化合物,其中:X代表硫原子或氧原子; R 1,R 2和R 3相同或不同,分别表示氢原子,硝基,氰基,-CO-R基团(其中R表示C 1 -C 4烷基或三氟甲基),氨基,乙酰胺基(NHCOCH3),C1-C4烷氧基,三氟甲基或被一个或多个氰基,硝基或三氟甲基取代的苯基,R1和R2可能一起形成,与它们所键合的苯基一起的β-萘基未被取代或被一个或多个氰基,硝基或三氟甲基取代; Y表示氢原子或脂肪族酰基。这些化合物可用作治疗剂,特别是用作静脉抗血栓药。

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