ASYMMETRIC SYNTHESIS OF FURO(3,4-C) PYRIDINE DERIVATIVES.

摘要

THE INVENTION RELATES TO A METHOD FOR THE PREPARATION OF A NON-RACEMIC FURO [3,4-C] PYRIDINE DERIVATIVES OF THE FORMULA 1 WHEREIN R1, R2 AND R3 STAND FOR VARIOUS SUBSTITUENTS, COMPRISING ADDING A CONCENTRATED STRONG ACID TO A SOLUTION OF A NON-RACEMIC COMPOUND OF THE FORMULA II IN AN AMOUNT SUFFICIENT TO CATALYSE A DEPROTECTION/ CYCLODEHYDRATION.