use of cytokine muteine natural immunogeni for the preparation of pharmaceutical compositions for treating or preventing diseases caused by overproduction of these cytokines, naturaland pharmaceutical compositions that can be obtained

摘要

Cytokines, including muteins thereof, which are biologically inactive in humans but remain immunogenic, are used in pharmaceutical compositions to promote a neutralizing immune response against native cytokines when administered to a subject in need thereof to treat homeostatic disorders and disorders associated with an overproduction of cytokines.