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Process for the production of crystalline forms of salts of lithium, potassium and magnesium citidindifosfocolina, the thus obtained crystalline forms and pharmaceutical use.

机译:柠檬酸锂,钾和镁的结晶形式的生产方法,由此获得的结晶形式和药学用途。

摘要

Process for the production of crystalline salt forms CITIDINFOSFOCOLINA (CYTICOLINA) monovalent cation LI, KY WITH CATION bivalent MG. The process involves salting of citicoline in free acid form with oxides, hydroxides, carbonates or bicarbonates their cations and crystallization of the salts with acetone. The novel crystalline forms obtained can be used advantageously in the treatment of diseases SLIP NERVOUS SYSTEM.
机译:结晶盐形式CITIDINFOSFOCOLINA(CYTICOLINA)单价阳离子LI,KY和CATION二价MG的生产方法。该方法涉及将游离酸形式的胞磷胆碱与它们的阳离子的氧化物,氢氧化物,碳酸盐或碳酸氢盐盐化,并用丙酮使盐结晶。所获得的新的结晶形式可以有利地用于疾病滑动神经系统的治疗。

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