A process for preparing particles stabilized epitopes for use as standards and controls for immunoassay of an antigenic substance.

摘要

The invention relates to a process for preparing standards and controls for immunoassays employing antibodies monochloro. These are used to isolate a portion RESTRICTED an antigen containing an epitope, which determines the specificity of the antibody-antigen reaction MONOCLONAL, SO THAT STANDS THIS antigen as a whole, FOLLOWED fragmentation of the antigen by methods They INCLUDE proteolysis. ISOLATED epitopes are covalently attached or by adsorbing PARTICLE PHYSICS A immobilizing and stabilizing the epitope. The particles can be composed of iodipamide ethyl ether, polyvinyl chloride POLYSTYRENE AND OTHER CARRIERS, AND MAY BE CHEMICALLY ACTIVOR UNION TO IMPROVE AND STABILITY Epitope. EXPERIMENTAL DETAILS SHOWN THE LINK Lipoprotein A IDE, polyvinyl chloride and polystyrene, and subsequent reaction monoclonal antibody epitopes THESE stabilized particles. This invention is particularly useful for measuring lipoprotein COMPONENTS ASSOCIATED WITH CHOLESTEROL, and includes an immunoassay kit MONOCLONAL BASE FOR MEASURING COMPONENTS IN FLUIDS Lipoprotein BIOLPOGICOS to calculate risk RELACONADO WITH COMPLICATIONS OF CORONARY ARTERY DISEASE.