Cefadroxil and method for producing crystalline.

摘要

The invention relates to a novel cefadroxil hemihydrate CRYSTALLINE HAVING A KF from 3.5 to 2.0%, which is more stable cefadroxil other molecules. NEW CEFADROXIL it obtained by preparing and isolating a dimethylamide NEW Solvate n-methyl-2-pyrrolidone OR MOMETILFORMAMIDA, SUCH SOLATO by slurrying with a mixture of methanol: Isopropanol BETWEEN 30:70 AND 70:30, BY VOLUME , in GODS presence of an amount of water between 5 and 12%, at a temperature of 45 to 55 degrees CY then filtering the compound thus obtained.