Method for determining the endogenous thrombin potential of plasma and blood, and also a computer for use in said method.

摘要

This method shows how much and how long Thrombin has been active in the sample of blood or plasma. ETP CAN BE USED TO DETERMINE THE EFFECTIVENESS OF Antithrombotic treatment of some kind. Such determination ETP UNDERSTANDS, adding to said sample, a thrombin substrate, an activator of thrombin formation, preparation protease inhibitor and if desired a drug of analysis. Thrombin substrate CHOOSE not to consume FULLY amount of thrombin generated in the sample; TO HAVE A NUMBER OF CONVERSION proportional to the amount of thrombin substrate present; AND HAVE A PRODUCT RESULTING CONVERSION CONVERSION measurable thrombin. THE DETERMINATION OF THE QUANTITY OF PRODUCT OF CONVERSION, LEADS TO THE DETERMINATION OF ETP. SELECTING THE TRIGGER EFFECT DETERMINED IF THE MEASURED ON INTRINSIC SYSTEM OR EXEMPLARY Clots makes it possible to determine the effect of the drug being analyzed PARTIES ON DELSISTEMA clot.