A bi-leaflet prosthetic heart valve comprises an essentially circular val ve ring (20), defining a circle and a valve ring plane (44), and having an internal circumference (21) which defines a flow channel (24) for the flow of blood. Further said bi-leaflet prosthetic heart valve comprises an axle (90) and two essentially half-moon-shaped valve leaflets (50, 70), both of which pivot independently of each other on said common axle (90), and being enabled - depending on the direction of blood flow - to assume an open position wherein both leaflets (50, 70) extend essentially at right angles to the valve ring plane (44), and to assume a closed po- sition wherein both leaf-lets (50, 70) extend essentially parallel to the valve ring plane (44) and virtually occlude the flow channel (24) with their combined areas. In order to offer the surgeon an additional possi- bility of influencing the flow conditions, the axle (90) extends excentri- cally, that is parallel to and at a distance from a diameter of said circle as defined by the valve ring (20). Further, one leaflet (70) comprises a larger area (75) than the area (55) of the other leaflet (50). Preferably, the leaflet (70) of larger area may occlude about 55 % to 80 % of a flow channel cross-section (25) and the leaflet (50) of smaller area may occlude about45 % to 20 % of the flow channel cross-section (25).
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