NUCLEIC ACID ENCODING INSULIN RECEPTOR SUBSTRATE-1 (IRS-1), IRS-1 PROTEIN, DISEASES, THERAPY ASSOCIATED WITH THE METABOLISM OF IRS-1.

摘要

the invention relates to a purified nucleic acid consisting essentially of nucleic acid encoding insulin receptor substrate 1 (irs-1); to prepare polypeptide purified irs; diagnosis of diseases associated with insulin, which are to measure an aspect of the m u00e9tabolisme of irs-1, diagnosis of a disease associated with the insulin was observed in one patient.who is to determine the structure of the irs-1 gene and analysis of the effect of a therapeutic agent which alters its ability to phosphorylate a tyrosine kinase as a substrate; and a method of treating in a mammal suffering from a disease caused by the thermal word of the irs - 1; and the application of a treatment in a mammal suffering from a disease caused by the phosphorylation substrate for tyrosine kinase.