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ENANTIOSELECTIVE PRODUCTION OF CHIRAL CARBOXYLIC ACIDS
ENANTIOSELECTIVE PRODUCTION OF CHIRAL CARBOXYLIC ACIDS
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机译:手性羧酸的对映体生产
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摘要
A process for enantioselectively converting an aldehyde, a bisulfite adduct of an aldehyde or a glycidate to a chiral carboxylic acid is disclosed. The process utilizes a microorganism or an enzyme preparation from a microorganism and is particularly useful for producing NSAIDs of the profen class from readily available precursors. Preferred microorganisms are Gram-negative rod bacteria.
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