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A 2,6-Methano-2H-quinolizin derivative as 5-HT3-receptor antagonist as a 5-HT3-receptor antagonist

机译:2,6-Methano-2H-quinolizin衍生物作为5-HT3受体拮抗剂作为5-HT3受体拮抗剂

摘要

The present invention relates to a novel 5HT3-5-chloro-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acid-octahydro-3-hydroxy-2,6-methano-2H-Quinolizin-8-yl ester, a process for the preparation thereof, and a method for the treatment of nausea and vomiting induced by radiotherapy and chemotherapy, for the treatment of pain associated with migraine, for treatment of cognitive disorders, for patients of schizophrenia and mania To the treatment of endogenous psychosis, to the treatment of excitatory bowel syndrome and to the use thereof in the treatment of substance abuse.
机译:本发明涉及一种新颖的5HT 3 -5-氯-2,3-二氢-2,2-二甲基苯并呋喃-7-羧酸-八氢-3-羟基-2,6-甲基- 2H-喹诺嗪-8-酯,其制备方法以及放射治疗和化学疗法引起的恶心和呕吐的治疗方法,用于治疗偏头痛相关的疼痛,认知障碍的治疗,精神分裂症和躁狂症用于治疗内源性精神病,用于治疗兴奋性肠综合症及其在药物滥用治疗中的用途。

著录项

  • 公开/公告号KR1019957000297A

    专利类型

  • 公开/公告日1995-01-16

    原文格式PDF

  • 申请/专利权人 스티븐 엘.네스비트;

    申请/专利号KR1019940702945

  • 发明设计人 모리스 더블유.짓토스;

    申请日1994-08-24

  • 分类号C07D471/18;A61K31/435;

  • 国家 KR

  • 入库时间 2022-08-22 04:12:19

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