where R1 and R2 are similar or different and mean C1-C3-alkyls, Na or K; R1 - means hydrogen or methyl; R2 - means hydrogen, C1-C3-alkyl, benzyl or thiomethyl, or R1 and R2 together form alkylene chain. Compounds showed as excellent inhibitors of proline- and lysine hydroxylase, fibro- or immune depressants, curative agents at collagen and collagen-like substances metabolism disorder. EFFECT: enhanced effectiveness of inhibitors indicated above. 1 tbl"/> INHIBITORS OF PROLINE- OR LYSINE HYDROXYLASE, FIBRO- OR IMMUNE DEPRESSANTS, CURATIVE AGENT USED AT DISORDERS OF COLLAGEN OR COLLAGEN-LIKE SUBSTANCES METABOLISM
首页> 外国专利> INHIBITORS OF PROLINE- OR LYSINE HYDROXYLASE, FIBRO- OR IMMUNE DEPRESSANTS, CURATIVE AGENT USED AT DISORDERS OF COLLAGEN OR COLLAGEN-LIKE SUBSTANCES METABOLISM

INHIBITORS OF PROLINE- OR LYSINE HYDROXYLASE, FIBRO- OR IMMUNE DEPRESSANTS, CURATIVE AGENT USED AT DISORDERS OF COLLAGEN OR COLLAGEN-LIKE SUBSTANCES METABOLISM

机译:脯氨酸或赖氨酸羟化酶抑制剂,纤维或免疫抑制剂,胶原蛋白或类似胶原蛋白物质代谢紊乱的治疗剂

摘要

FIELD: organic chemistry. SUBSTANCE: method involves the use of derivatives of oxalylamino acids of the formula (I) where R1 and R2 are similar or different and mean C1-C3-alkyls, Na or K; R1 - means hydrogen or methyl; R2 - means hydrogen, C1-C3-alkyl, benzyl or thiomethyl, or R1 and R2 together form alkylene chain. Compounds showed as excellent inhibitors of proline- and lysine hydroxylase, fibro- or immune depressants, curative agents at collagen and collagen-like substances metabolism disorder. EFFECT: enhanced effectiveness of inhibitors indicated above. 1 tbl
机译:领域:有机化学。实质:该方法涉及使用式(I)的草酰氨基酸衍生物。其中R 1 和R 2 相似或不同,均表示C 1 -C 3 -烷基,Na或K; R 1 -表示氢或甲基; R 2 -表示氢,C 1 -C 3 -烷基,苄基或硫代甲基或R 1 和R 2 一起形成亚烷基链。化合物表现出出色的脯氨酸和赖氨酸羟化酶抑制剂,纤维抑制剂或免疫抑制剂,胶原蛋白治疗剂和胶原蛋白样物质代谢障碍。效果:增强了上述抑制剂的有效性。 1汤匙

著录项

相似文献

  • 专利
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号