New carboxymethylidene cycloheptimidazole derivatives, processes for their preparation and their use as antihypertensive and anticongestive agents

摘要

New therapeutic agent of carboxymethylidenecycloheptimidazole derivatives and method for the manufacture thereof are disclosed, which are represented by the following formula or its alkali addition salts IMAGE (1) (wherein R1 represents a lower alkyl; R2 represents H or isopropyl group; R3 represent H, a lower alkyl or -C(CH3)H-OCOOR4 (R4 is a lower alkyl or cyclohexyl) and =CHCOOR3 is substituted group at 4 or 8 position; A represents IMAGE These compounds are useful as anti-hypertensive, anti-congestive heart failure agents and intraocular pressure lowering agents.