Novel peptides, directed antibodies against these peptides, application by way of medicinal products, pharmaceutical compositions containing them and diagnostic kits.

摘要

Peptide monomers (I), recognised by a humoral or cellular immune response and producing a auto-immune reaction in subjects infected with HIV-1 or -2 are of formulae: SLWDQ (1) SLWDQSLK (51) DIISLWDQSLD (3) HEDIISLWDQSLKPCVK (46) VEINCTRR1R2N (22) FR3CNST (24) YVGSR4LEI (27) PLTEEA (29) QGQWTR5Q (30) RR6GVETTTPS (48) EALKYW (34) CNSTV (26) EETAGVVSTN (50) VVSTNLIRNG (14) VEINCTR (37) INCTR (52); R1-R2 = T-Q or P-N; R3 = Y or F; R4 = D or N; R5 = Y or Q; R6 = S or A. Opt. (I) also have 1-5 amino acids more at C and/or N termini and also included are multimers having 2-6 (I) units in a linear chain.