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A strain of Streptomyces lavendofoliae DKRS and its use in producing aclacinomycins A,B,Y and aglycone

机译:薰衣草链霉菌DKRS菌株及其在生产阿克拉霉素A,B,Y和糖苷配基中的应用

摘要

Disclosed herein are a novel strain of Streptomyces and a method for the production of aclacinomycins A, B, Y and aglycone thereof by cultivating the same. Streptomyces lavendofoliae DKRS (KCTC 00928P) of the present invention is capable of producing aclacinomycins A, B, Y and aglycone with higher yield. Further, it is possible to selectively produce aclacinomycin Y or A by adjusting pH of the cultured broth of Streptomyces lavendofoliae DKRS to 4.4 or 4.6 with acetate buffer or hydrochloric acid, respectively.
机译:本文公开了新的链霉菌菌株及其通过培养来生产阿克拉霉素A,B,Y及其糖苷配基的方法。本发明的薰衣草链霉菌DKRS(KCTC 00928P)能够以更高的产率生产阿克拉霉素A,B,Y和糖苷配基。此外,可以通过分别用乙酸盐缓冲液或盐酸将淡链霉菌DKRS的培养液的pH调节至4.4或4.6来选择性地产生阿克拉霉素Y或A。

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