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Human cell line stably expressing 5cDNAS encoding procarcinogen- activating enzymes and related mutagenicity assays
Human cell line stably expressing 5cDNAS encoding procarcinogen- activating enzymes and related mutagenicity assays
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机译:稳定表达编码致癌原激活酶的5cDNAS的人类细胞系和相关诱变分析
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摘要
An immortal human cell line stably expressing a multiplicity of cytochrome P450s is provided. Preferably, the cell line is MCL-5, which stably expresses cytochrome P450 IA1, IA2, IIA3, IIIA4, and IIE1, as well as microsomal epoxide hydrolase. The cell line is useful in mutagenicity, toxicity and metabolism studies.
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